Pemodelan Pola Perambatan Gelombang Kalsium Pada Jaringan Astrocyte Dengan Simulator Brian2

Authors

  • Itsnainiyah Hafizhoh
  • Anis Yuniati

Keywords:

Astrocyte, Li-Rinzel, Gap-Junction Channels, Simulator Brian2

Abstract

Calcium wave propagation pattern modeling has been successfully carried out in astrocyte network using Brian2 simulator. The astrocyte model is defined by the Li-Rinzel equation which involves the IP3Rs (q) activation fraction. IP3Rs activation fraction parameter (q) affects the value of calcium concentration in astrocytes. The connection between astrocyte is in the form of Gap-Junction Channels (GJCs). The variation in this modeling is the number of astrocyte cells stimulated by external currents in the astrocyte network being modeled. The modeling results show that the IP3Rs (q) activation fraction can affect the propagation of calcium waves in astrocytes through activation of IP3 receptors

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Published

2020-11-15

How to Cite

Hafizhoh, I., & Yuniati, A. (2020). Pemodelan Pola Perambatan Gelombang Kalsium Pada Jaringan Astrocyte Dengan Simulator Brian2. Sunan Kalijaga Journal of Physics, 2(2), 50–57. Retrieved from https://ejournal.uin-suka.ac.id/saintek/physics/article/view/2291

Issue

Vol. 2 No. 2 (2020): Sunan Kalijaga Journal of Physics

Section

Articles

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Copyright (c) 2021 Itsnainiyah Hafizhoh, Anis Yuniati

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This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.