Sintesis dan Karakterisasi Kompleks Zn (II) dengan Schiff Base: Aplikasi dan Optimasi Kondisi Reaksi - Review
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Abstract
Kompleks Zn(II)–Schiff base merupakan sistem koordinasi yang menarik karena stabilitas tinggi, sifat fluoresensi, serta potensi aplikasi dalam bidang biologi dan material. Artikel ini meninjau berbagai metode sintesis kompleks Zn(II)–Schiff base melalui reaksi kondensasi ligan organik dengan garam Zn(II), yang umumnya dilakukan dalam pelarut polar dengan kondisi refluks terkontrol. Karakterisasi dilakukan menggunakan FTIR, NMR, UV-Vis, analisis unsur, dan difraksi sinar-X, serta diperkuat dengan kajian komputasi Density Functional Theory (DFT), yang konsisten menunjukkan koordinasi Zn(II) melalui gugus imina dan fenolat dengan geometri tetrahedral terdistorsi. Aplikasi kompleks ini meliputi aktivitas antibakteri terhadap Salmonella typhi, E. coli, dan S. aureus, sifat fluoresensi untuk sensor optik, fotostabilisasi polimer, serta potensi sebagai prekursor ZnO nanopartikel dan material semikonduktor. Hasil tinjauan menegaskan bahwa optimasi kondisi reaksi—terutama pemilihan pelarut, rasio ligan-logam, waktu refluks, dan pH—merupakan faktor kunci untuk memperoleh rendemen tinggi, stabilitas kompleks, dan efektivitas aplikasi.
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